Current Research Projects

Hopeful Heart Trial

The Hopeful Heart Trial is an NHLBI-funded study that aims to examine if treating depression and heart failure together is more effective at improving health-related quality of life than treating heart failure alone.

Online Treatment Trial

The Online Treatment Trial is an NIMH-funded trial that tested the effectiveness of a computerized cognitive behavioral therapy program and Internet support group provided by a collaborative care strategy.


The ETUDES Center is an ALACRITY Center (P50) grant funded by the NIMH to help professionals in pediatric primary care better support youth who may be experiencing depression or suicidality.


OPTIMUM is a PCORI-funded research study designed to test which medications work best and are safest for adults age sixty and older with difficult-to-treat depression.

COVID-19 Vaccine Hesitancy Research

Center Members, Dr. Sidani and Ms. Hoffman have worked extensively on COVID-19 Vaccine Hesitency Research during the Coronovirus Pandemic. Read more about their work and hear their presentations here. 


The CaRISMA Study is a PCORI-funded research project that aims at providing better treatments and better pain care for people with Sickle Cell Disease (SCD) that do not rely only on opioids/narcotics or other medications.